Study of the catecholamine transmission in rat and mouse brain through the “in vivo” assessment of dopamine and norepinephrine by the microdialysis method focusing on the effect of drugs of abuse, antidepressants and antipsychotics. Study of the catecholamine transmission in animal models of Attention Deficit with Hyperactivity Disorder (ADHD) and animal models of depression. Study of the effect of prenatal stress on the catecholamine transmission in adolescent and adult offspring.

Ezio Carboni was born in 1955. He has received his degree in Pharmacy and the Ph.D. in Toxicology from the University of Cagliari. He has been post-doc and/or researcher at the NIMH, at the University of Georgetown in Washington D.C. and at the University of California in Irvine. He has taught Toxicology and Pharmacology from 1995 to date in the school of Pharmacy of the University of Cagliari.

Ezio Carboni, Maria T.P. Rolando, Alessandra Silvagni and Gaetano Di Chiara. INCREASE OF DIAYSATE DOPAMINE IN THE BED NUCLEUS OF STRIA TERMINALIS BY CLOZAPINE AND RELATED NEUROLEPTICS. Neuropsychopharmacology Vol 22, n° 2 pp 140-147; 2000.
Ezio Carboni, Luana Bortone, Corrado Giua and Gaetano Di Chiara. DISSOCIATION OF PHYSICAL ABSTINENCE FROM CHANGES IN EXTRACELLULAR DOPAMINE IN THE NUCLEUS ACCUMBENS AND IN THE PREFRONTAL CORTEX OF NICOTINE DEPENDENT RATS. Drug and Alcohol dependence , Vol. 58, pp 93-102; 2000.
Ezio Carboni, Alessandra Silvagni, Maria T. P. Rolando and Gaetano Di Chiara. STIMULATION OF IN VIVO DOPAMINE TRANSMISSION IN THE BED NUCLEUS OF STRIA TERMINALIS BY REINFORCING DRUGS. Journal of Neuroscience. Vol 20, RC102 pp1-5, (2000).
Carboni E., Spielowoy C., Vacca C., Nosten-Bertrand M., Giros B. and Di Chiara G. COCAINE AND AMPHETAMINE INCREASE EXTRACELLULAR DOPAMINE IN THE NUCLEUS ACCUMBENS OF MICE LACKING THE DOPAMINE TRANSPORTER GENE. Journal of Neuroscience. Vol 21, RC141 pp 1-4 2001
Carboni E., Vacca C., Giros B., and Di Chiara G. ROLE OF DOPAMINE AND NOREPINEPHRINE TRANSPORTER IN THE EFFECT OF COCAINE: A MICRODIALYSIS STUDY. In Monitoring Molecules in Neuroscience. O’Connor W., Lowry P.J., O’Connor J.J. O’Neill R.D. Eds. University College of Dublin. Dublin 2001
Ezio Carboni MICRODIALYSIS COUPLED WITH ELECTROCHEMICAL DETECTION: A WAY TO INVESTIGATE BRAIN MONOAMINE ROLE IN FREELY MOVING ANIMALS. In Methods in Molecular Medicine, Vol. 78: Drugs of Abuse: Neurological Reviews and Protocols. John Q.Wang Ed. pp 415-432. Humana Press Inc. Totowa NJ. 2003.
Ezio Carboni, Cinzia Vacca CONDITIONED PLACE PREFERENCE: A SIMPLE METHOD FOR INVESTIGATING REINFORCING PROPERTIES IN LABORATORY ANIMALS. In Methods in Molecular Medicine, Vol. 78: Drugs of Abuse: Neurological Reviews and Protocols. John Q.Wang Ed. pp 481-498. Humana Press Inc. Totowa NJ. 2003.
E. Carboni, A. Silvagni, V. Valentini and G. Di Chiara: A MICRODIALYSIS STUDY OF DOPAMINE TRANSMISSION IN THE NUCLEUS ACCUMBENS SHELL OF SHR RATS: A MODEL OF ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD). In Monitoring Molecules in Neuroscience Kehr J., Fuxe K., Ungersted U. Svensson T. Eds. Karolinska University Press, Stockholm, Sweden, pp. 76-78, 2003.
Silvagni A., Carboni E., Vacca C. and Di Chiara G.: EFFECT OF DOPAMINE AND NOREPINEPHRINE CARRIER BLOCKADE ON EXTRACELLULAR DOPAMINE RELEASE IN RAT BRAIN. In Monitoring Molecules in Neuroscience Kehr J., Fuxe K., Ungersted U. Svensson T. Eds. Karolinska University Press, Stockholm, Sweden, pp. 374-376, 2003.
Carboni E., Silvagni A., Valentini V., and Di Chiara G..EFFECT OF AMPHETAMINE, COCAINE, AND DEPOLARIZATION BY HIGH POTASSIUM ON EXTRACELLULAR DOPAMINE IN THE NUCLEUS ACCUMBENS SHELL OF SHR RATS. AN IN VIVO MICRODYALISIS STUDY. Neurosciences and Biobehavioral Reviews vol. 27, pp 653-659, 2003.
Ezio Carboni and Alessandra Silvagni. EXPERIMENTAL INVESTIGATION ON DOPAMINE TRANSMISSION CAN PROVIDE CLUES ON THE MECHANISM OF ACTION OF AMPHETAMINE AND METHYLPHENIDATE IN ADHD. Neural plasticity vol. 11 pp 77-95, 2004
Ezio Carboni, Alessandra Silvagni. DOPAMINE REUPTAKE BY NOREPINEPHRINE NEURONS. EXCEPTION OR RULE? Critical Reviews in Neurobiology vol. 16 pp 121-128, 2004.
Di Chiara G, Bassareo V, Fenu S, De Luca MA, Spina L, Cadoni C, Carboni E, Valentini V, Lecca D. DOPAMINA AND DRUG ACTION: THE NUCLEUS ACCUMBENS SHELL CONNECTION. Neuropharmacology vol. 47 supp. 1, pp 227-241 (2004).
Ezio Carboni, Alessandra Silvagni, Cinzia Vacca, Gaetano Di Chiara. CUMULATIVE EFFECT OF NOREPINEPHRINE AND DOPAMINE CARRIER BLOCKADE ON EXTRACELLULAR DOPAMINE INCREASE IN THE NUCLEUS ACCUMBENS SHELL, BED NUCLEUS OF STRIA TERMINALIS AND PREFRONTAL CORTEX. Journal of Neurochemistry vol. 96 pp 473-481 (2006)